{"id":6450,"date":"2019-10-14T08:53:58","date_gmt":"2019-10-14T12:53:58","guid":{"rendered":"https:\/\/www.simonssearchlight.org\/?page_id=6450"},"modified":"2019-10-14T08:53:58","modified_gmt":"2019-10-14T12:53:58","slug":"6450-2","status":"publish","type":"page","link":"https:\/\/www.simonssearchlight.org\/research\/what-we-study\/syngap1-old\/6450-2\/","title":{"rendered":""},"content":{"rendered":"<h2><strong>A polygenic burden of rare disruptive mutations in schizophrenia<\/strong><\/h2>\n<p>Original research article by S.M. Purcell\u00a0<em>et al.<\/em> (2014).<\/p>\n<p>Read the article <a href=\"https:\/\/www.nature.com\/articles\/nature12975\">here<\/a>.<\/p>\n<p>This study screened over 5,000 individuals from a population in Sweden for about 2,500 genes that are candidates for autism and intellectual disability. One patient diagnosed with autism was found to have a mutation in SYNGAP1 that was not present in either parent (<em>de novo<\/em>).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A polygenic burden of rare disruptive mutations in schizophrenia Original research article by S.M. Purcell\u00a0et al. (2014). Read the article here. This study screened over 5,000 individuals from a population in Sweden for about 2,500 genes that are candidates for autism and intellectual disability. One patient diagnosed with autism was found to have a mutation [&hellip;]<\/p>\n","protected":false},"author":13,"featured_media":0,"parent":588,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"acf":[],"_links":{"self":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/6450"}],"collection":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/comments?post=6450"}],"version-history":[{"count":1,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/6450\/revisions"}],"predecessor-version":[{"id":6451,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/6450\/revisions\/6451"}],"up":[{"embeddable":true,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/588"}],"wp:attachment":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/media?parent=6450"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}