{"id":6177,"date":"2019-09-26T08:42:37","date_gmt":"2019-09-26T12:42:37","guid":{"rendered":"https:\/\/www.simonssearchlight.org\/?page_id=6177"},"modified":"2019-09-26T08:42:37","modified_gmt":"2019-09-26T12:42:37","slug":"6177-2","status":"publish","type":"page","link":"https:\/\/www.simonssearchlight.org\/research\/what-we-study\/grin2b-2\/6177-2\/","title":{"rendered":""},"content":{"rendered":"<h2><strong>Multiplex targeted sequencing identifies recurrently mutated genes in autism <\/strong><strong>spectrum<\/strong><strong> disorders<\/strong><\/h2>\n<p>Original research article by B.J. O\u2019Roak <em>et al.<\/em> (2012)<\/p>\n<p>Read the abstract <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23160955\">here<\/a>.<\/p>\n<p>The authors of this study used genetic material from 2,446 people in the Simon Simplex Collection (SSC) to look for 44 genes that have been associated with autism. The SSC includes children with autism and intellectual disability. This study identified 27 de novo (not inherited from either parent) gene changes in 16 genes, including four people with changes in\u00a0<em>GRIN2B<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders Original research article by B.J. O\u2019Roak et al. (2012) Read the abstract here. The authors of this study used genetic material from 2,446 people in the Simon Simplex Collection (SSC) to look for 44 genes that have been associated with autism. The SSC includes [&hellip;]<\/p>\n","protected":false},"author":13,"featured_media":0,"parent":502,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"acf":[],"_links":{"self":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/6177"}],"collection":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/comments?post=6177"}],"version-history":[{"count":1,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/6177\/revisions"}],"predecessor-version":[{"id":6178,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/6177\/revisions\/6178"}],"up":[{"embeddable":true,"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/pages\/502"}],"wp:attachment":[{"href":"https:\/\/www.simonssearchlight.org\/wp-json\/wp\/v2\/media?parent=6177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}